Disperse chart for participant options. In this data, i counted the fresh urinary Na/K ratio and BP inside several,890 professionals (84% out of professionals have been out-of 2017) for two years. In the end, several,877 participants was basically analyzed
Na/K proportion
Tome Area asked participants to collect its pee examples shortly after waking have always been. The new urinary Na/K proportion is actually measured using a urinary Na/K ratio-measuring equipment named HEU-001F (OMRON Medical care Co., Ltd., Kyoto, Japan) (Additional Fig. 1). The newest display screen instantly ideas urinary Na/K ratio proportions. A public nurse mentioned the Na/K proportion from the place pee types of the players having fun with the machine, recorded the importance, and you can provided instant viewpoints towards members about your counted really worth and explanatory question concerning the dating within urinary Na/K proportion and you can BP (Additional Fig. 2). Tome Town works fitness check-ups within the each district from year to year out of Could possibly get to help you Sep. Hence, users have its urinary Na/K proportion mentioned at the same time in both 2017 and you may 2018.
Most other proportions
Information regarding almost every other dimensions try obtained from medical checkup research from Tome Area. One another fat and the entire body peak were counted from inside the wellness checkup. Bmi are determined because lbs (kg)/height dos (meters 2 ). BP is actually measured twice of the a tuned social health nursing assistant. Since the fitness checkup studies available with Tome Urban area merely integrated the lower BP measurement of the two BP measurement viewpoints, we are able to only were this really worth in our data. Blood pressure level is recognized as systolic BP (SBP) ? 140 mmHg otherwise diastolic BP (DBP) ? 90 mmHg and you will/and/or usage of antihypertensive procedures. Information on liquor consumption is actually acquired of the a survey. I calculated the brand new alcoholic beverages intake weekly as follows: we increased this new frequency away from alcohol based drinks (every day = 7, possibly = 3.5, with no habitual ingesting = 0) and you may quantity of liquor taken in a single celebration (0–step 1 drink = 0.5, 1–dos products = step one.5, 2–step 3 beverages = 2.5, and 3 beverages or higher = 3) and you will separated the product by eight. One to take in inside The japanese represents 23 grams away from ethanol. Studies towards the use of diabetic issues therapy and you will way to heart state was in fact notice-advertised on health checkup research.
With regard to information on the effective use of diabetes procedures, users chose that alternative from the adopting the answers: (a) a track record of diabetes, (b) around answer to all forms of diabetes mellitus, otherwise (c) accessibility all forms of diabetes medication. People that replied (c) have been categorized while the “users off all forms of diabetes cures,” whereas people who answered which have (a) otherwise (b) or otherwise not relevant was categorized because “others.” With regard to information on the treatment to possess heart disease, people chose one to solution regarding adopting the solutions: (a) has a history of heart disease otherwise (b) being treated to possess cardiovascular disease. Individuals who replied (b) had been classified because the “undergoing treatment for heart problems,” whereas people who replied which have (a) or perhaps not relevant had been classified as the “anyone else.”
Statistical study
To compare the difference between participants who attended health checkups both in 2017 and 2018 and those who attended health checkups only in 2017, we used the t-test for continuous variables and the chi-square test for categorical variables. For each year firstmet nedir, we compared the baseline characteristics according to the urinary Na/K ratio level. Moreover, we analyzed the relationship between the urinary Na/K ratio and hypertension adjusted for age, sex, BMI, alcohol intake, use of diabetes medication, and treatment for heart disease. For longitudinal data, we assessed the relationship between change in urinary Na/K ratio and BP change using multiple regression analyses adjusted for age, sex, BMI change, and alcohol intake. In both cross-sectional and longitudinal analyses, we stratified the data according to the use of antihypertensive medication. We further added SBP or DBP in 2017 as a covariate. Furthermore, we analyzed the BP difference according to the urinary Na/K ratio quartile in 2017. To examine the effect of BP due to temperature, we acquired past temperature data from the Japan Meteorological Agency in 2017 and 2018 . We considered P < 0.05 as statistically significant.
