Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men's body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.
Inclusion
The new frequency away from infertility certainly people out-of reproductive age brackets, predicated on various supply, out-of 8% to help you twenty five% [1–3]. Male infertility is the only cause of sterility in the 20–30% out-of circumstances and something leading to infertility inside the fifty% of all of the sterility instances . The newest research of male fertility always is sold with medical examination and you may assessment to your resource opinions of adopting the sperm details: volume, full sperm count, concentration, motility and you will morphology (Table step 1) . Reduced sperm fertility and you can/otherwise top quality exists inside the ninety% of people with fertility difficulties . From the analysis regarding virility, the latest density off men reproductive hormonal also are examined. Now, this new unit constitution regarding spunk structure, assessed of the evaluating the level of DNA fragmentation otherwise oxidative be concerned could have been increasingly considered. Multiple degree utilize the DNA fragmentation directory (DFI) while the an indication of being pregnant achievements. Centered on Evenson and you may Wixon, DFI ranges off 3 to 5% in healthy men, while you are a beneficial DFI out of ? 30% is for the faster virility . Currently laid out hereditary facts, also each other chromosomal aberrations and you may monogenic change, account fully for no more than 10–15% of cases of men infertility . The cause to own virility issues can certainly be environmental escort in Fargo ND situations. The goal of the analysis were to get to know the relationship anywhere between eating plan, times balance and you may fertility pricing when you look at the boys.
Method out-of literary works lookup
A comprehensive literature search of published studies in various languages, was carried out in electronic databases, including: PubMed, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Review and Google Scholar. Randomized controlled trials, observational and qualitative studies published between 2008 and 2018 (up to and including March) were included. The following keywords related to male infertility, diet, nutrients and their combinations (made by applying operators AND and OR) were used in the search: ‘male infertility’, ‘sperm quality’, ‘idiopathic oligozoospermia’, ‘astenoazospermia’, ‘oligoastenoteratozoospermia’, ‘sperm DNA damage’, ‘nutritional status’, ‘BMI’, ‘obesity’, ‘diet’, ‘nutrition’, dietary pattern’, ‘food’, ‘nutrient’, ‘fatty acids’, ‘antioxidant’, ‘supplementation’, ‘vitamin C’, ‘vitamin E’,’ vitamin A’, ‘folate’, ‘zinc’, ‘selenium’, ‘L-carnitine’, ‘glutathione’, ‘coenzyme Q10‘, ‘N-acetylcysteine’, ‘lycopene’. Reference lists of studies extracted from the primary electronic search were used to identify additional relevant studies.
| Sperm factor | Resource limit (95% believe periods) |
|---|---|
| Sperm frequency | step 1.5 ml (1.4–step one.7) |
| Overall sperm fertility | 39 million per squirt (33–46) |
| Jizz concentration | 15 mil each ml (12–16) |
| Vitality | 58% live (55–63) |
| Modern motility | 32% (31–34) |
| Complete (modern + nonprogressive) motility | 40% (38–42) |
| Morphologically normal models | 4.0% (step three.0–4.0) |
