21 The month of january: “–pull range” and “–exclude range” don’t error out whenever its type in documents have an effective chromosome password absent on the newest dataset.
: Fixed –meta-analysis-se-industry bug. –meta-analysis-chr-community and you can –meta-analysis-bp-career flags extra. On the creativity generate, –dfam consistently errors away that have a suitable message, in the place of maybe segfaulting, whenever no legitimate times exist.
twenty-eight October: –meta-analysis-se-community banner additional, to have interoperation with present PLINK 2.0 logistic regression efficiency (hence uses an effective ‘LOG(OR)_SE’ community title to help you disambiguate the standard error’s tools).
Fixed “–design gen” permutation investigations insect
24 October: Fixed uninitialized-varying bug from inside the –dose + –q-score-range. “–indep-pairwise 500kb . ” really works safely once again (the prior create required a space till the ‘kb’).
cuatro Mar: Supports inside order-line let text message are actually utilized in a way much more similar to many other systems. –evaluating now work safely whenever a great numeric dispute was 1 early in the day the conclusion.
twenty six Could possibly get (beta six): –merge-equal-pos bugfixes. If you utilized –merge-equal-pos that have .bed+.bim+.fam filesets in which allele buy could have differed between .bim data files, or that have any .ped+.chart fileset anyway, we advice redoing that run.
: –meta-investigation ‘report-all’ today reports new statistics rather than ‘NA’ when N=1. Repaired an inaccuracy for the –adjust’s management of very small p-opinions. –make-just-fam really works securely in just .fam enter in once more.
14 The fall of (beta 5): –file + –merge[-list] bugfix. map document try unsorted, but when you have the chance i encourage redoing one –file + –mix and you may –document + –merge-record multiple-.ped merges did with earlier plink step 1.9 generates. (.bed merging is unaffected, and you may –merge-record rather than –document is very nearly never ever influenced.)
15 Oct: A2 allele has grown to become constantly resource on the chr3 in our 1000 Genomes phase step one downloads. In most cases, you should not be prepared to remain REF/ALT alleles straight with PLINK 1.x, but we made an effort to build A2 consistently resource on these documents but still didn’t a little make it; disappointed about this. (As to why try so it found today, more 2.five years adopting the fact? Once the PLINK 2.0 presently has an excellent –ref-from-fa flag that may without difficulty search for such error.)
13 Oct: “–freq counts” no more gets reversed overall performance whenever alleles was in fact flipped of the original .bim/.bed order. Repaired –logistic bug that’ll end in spurious NA abilities.
7 October: Repaired place-situation (a couple of four haplotypes don’t have any identified observations) bug within the –ld/–r2/–blocks/–clump’s analytical phasing processes. 32-bit make are now able to types >2GB .bed data without crashing. –annotate and you will –gene-report today run –allow-extra-chr.
fifteen Aug: –lasso should today work effectively when there will be trials with covariates present nevertheless head phenotype forgotten.
21 May: “–linear communication intercourse” and you can “–logistic telecommunications gender” today work effectively whenever zero covariates are present. –tucc added to creativity make.
20 February (beta cuatro): –pca var-wts today records allele requirements. Minor mathematical phasing bugfix. –[max-]mac computer, –Roentgen, and you may –thin-indiv[-count] no more classified because the volatile. PLINK dos.0 leader stimulates are in fact available.
It bug is actually more inclined so you’re able to trigger in case your earliest
13 November: –geno/–shed today eradicate heterozygous haploid calls given that nonmissing; that is in keeping with –attention, and you may PLINK 1.07’s behavior which have –recode/–make-sleep energetic. They’re now inconsistent with what PLINK step one.07 did in place of –recode/–make-bed; use –make-bed + –set-hh-forgotten first if you need the outdated behavior. “–ci 0.95” not any longer produces ‘L94’/’U94’ line brands whenever plink gets unfortunate that have rounding. Small –exclude/–extract/–flip bugfix having type in records without newline at the bottom. –qfam[-within] bugfix. –dosage ‘sex’ modifier today functions securely when certain samples have been blocked aside (age.g. as certain phenotypes was basically lost).
20 September: VCF export no longer erases an alt cachondo haciendo amigos citas allele absent throughout the instant dataset, on account of a beneficial retroactive revision into VCF requirements.
